, 1994). CoVs genomic RNA replication is mediated by RNA-directed RNA polymerase (Pol/RdRp) which can be also to blame for transcription in the viral RNA genome. There is experimental proof for SARS-CoV that nsp7 and nsp8 activate and confer processivity into the RNA-synthesizing action from the polymerase (Walls et al., 2000). The synthesis of sub

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